白血病性网状内皮增生症。脾切除术后血小板缺陷的丧失。
Leukemic reticuloendotheliosis. Loss of platelet defect after splenectomy.
作者信息
Feiner A S, Meyers A M, Moore G E
出版信息
JAMA. 1978 Jul 21;240(3):238-40. doi: 10.1001/jama.240.3.238.
PMID:660848
Abstract
A 59-year-old woman with leukemic reticuloendotheliosis had pancytopenia and hypersplenism. Before splenectomy, she had an abnormal bleeding time and a severe defect of secondary-wave platelet aggregation. After splenectomy, the platelet count returned to normal, and the aggregation defect was no longer present. This response suggests that the spleen may contribute to the platelet dysfunction.
摘要
一名患有白血病性网状内皮细胞增生症的59岁女性出现全血细胞减少和脾功能亢进。脾切除术前，她的出血时间异常，继发性血小板聚集存在严重缺陷。脾切除术后，血小板计数恢复正常，聚集缺陷不再存在。这种反应表明脾脏可能导致血小板功能障碍。
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引用本文的文献
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Platelet function in hairy-cell leukaemia.毛细胞白血病中的血小板功能
J Clin Pathol. 1979 Aug;32(8):814-21. doi: 10.1136/jcp.32.8.814.
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