Baciewicz A M, Swafford W B
Drug Intell Clin Pharm. 1984 Apr;18(4):309-10. doi: 10.1177/106002808401800407.
Sulfonylureas hypoglycemic action may be potentiated by sulfonamides. This case report describes a 69-year-old female with a hypoglycemic episode suggestive of an interaction between chlorpropamide and sulfamethoxazole (co-trimoxazole). The patient had no renal or liver dysfunction. This interaction is rare but one should be aware of it, especially with combination products.
磺酰脲类药物的降血糖作用可能会被磺胺类药物增强。本病例报告描述了一名69岁女性发生低血糖发作，提示氯磺丙脲与磺胺甲恶唑（复方新诺明）之间存在相互作用。该患者无肾或肝功能障碍。这种相互作用很罕见，但人们应该对此有所认识，尤其是对于复方制剂。
