Electrical activity from cells in the whole, isolated, intact bovine pituitary gland. I. Changes induced by injection of hypothalamic, pineal and intraglandular colloid material.

Spontaneous electrical activity can be recorded from all lobes of the whole, isolated, intact bovine pituitary gland with subdermal electrodes. The potentials can be modified by injecting either crude hypothalamic, pineal gland or intraglandular colloid material. The pituitary cells yield grossly similar responses to these materials, and it is thought that the materials act through distinctly separate receptors.