Electrical activity from cells in the whole, isolated, intact bovine pituitary gland. II. Changes induced by injection of pentobarbital and morphine.

Spontaneous electrical activity can be recorded from certain pockets of cells in the whole, intact, isolated bovine pituitary gland. Other pockets of cells are either just noticeably active or electrically silent. An infusion of either pentobarbital or morphine enhanced spontaneous electrical activity and induced activity in electrically silent cells. An application of these agents resulted in an unprecedented excitatory response.