Franklin A, Horn af Rantzien M
Nord Vet Med. 1983 Dec;35(12):460-4.
The minimum inhibitory concentration (MIC) of ten antimicrobial drugs for 287 S. aureus strains recently isolated from bovine mastitic milk in different herds all over Sweden was determined. The minimum bactericidal concentration (MBC) of benzylpenicillin for 20 strains was determined. Thirty strains (10%) produced beta-lactamase. All strains were susceptible to oxacillin and neomycin, and more than 90% to streptomycin, trimethoprim-sulphamethoxazole chloramphenicol, erythromycin and tetracycline, whereas all were resistant to sulphamethoxazole. None of 20 strains investigated was tolerant to benzylpenicillin. However, S. aureus strains, isolated from bovine milk, should be tested for beta-lactamase production prior to treating mastitic cases with beta-lactam drugs.
测定了从瑞典各地不同牛群近期患乳房炎奶牛的乳中分离出的287株金黄色葡萄球菌对10种抗菌药物的最低抑菌浓度（MIC）。测定了20株菌对苄青霉素的最低杀菌浓度（MBC）。30株菌（10%）产生β-内酰胺酶。所有菌株对苯唑西林和新霉素敏感，对链霉素、甲氧苄啶-磺胺甲恶唑、氯霉素、红霉素和四环素的敏感率超过90%，而对磺胺甲恶唑均耐药。所研究的20株菌中无一株对苄青霉素耐受。然而，在用β-内酰胺类药物治疗乳房炎病例之前，应检测从牛乳中分离出的金黄色葡萄球菌是否产生β-内酰胺酶。
