Antoine J L, Aurias A, Dutrillaux B
Ann Genet. 1984;27(1):27-32.
A classification is proposed of the tri- and quadriradials, based on theoretical and observed anomalies induced by radiation. Mitotic consequences of radials during S-phase are analysed, and it is shown that the rate of induction of unbalanced rearrangements is very much higher than that of balanced ones. After extrapolation to germ cells, it can be assumed that irradiation during S-phase will induce a high risk of chromosome imbalance for progeny which will be restricted almost entirely to the first generation.
基于辐射诱发的理论和观察到的异常情况,提出了对三价和四价体的一种分类方法。分析了S期径向体的有丝分裂后果,结果表明不平衡重排的诱导率远高于平衡重排的诱导率。外推到生殖细胞后,可以假定S期照射会给后代带来染色体不平衡的高风险,而这种风险几乎完全局限于第一代。