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正电子发射断层扫描显示基底神经节异常的单纯性偏侧肌张力障碍。

Pure hemidystonia with basal ganglion abnormalities on positron emission tomography.

作者信息

Perlmutter J S, Raichle M E

出版信息

Ann Neurol. 1984 Mar;15(3):228-33. doi: 10.1002/ana.410150303.

Abstract

We present a patient with hemidystonia and an abnormality of the contralateral basal ganglion seen only with positron emission tomography. A 50-year-old sinistral man suffered minor trauma to the right side of his head and neck. Within 20 minutes he developed paroxysmal intermittent dystonic posturing of his right face, forearm, hand, and foot, with weaker contractions of the left foot, lasting several seconds and recurring every few minutes. Neurological findings between spells were normal. The following were also normal: electrolyte, calcium, magnesium, and arterial blood gas levels, and findings of drug screen, cerebrospinal fluid examination, electroencephalography with nasopharyngeal leads, computed tomographic scanning (initially and four weeks later), and cerebral angiography. Positron emission tomographic scanning revealed abnormalities in the left basal ganglion region, including decreased oxygen metabolism, decreased oxygen extraction, increased blood volume, and increased blood flow.

摘要

我们报告了一名患有偏侧肌张力障碍的患者,其对侧基底神经节异常仅通过正电子发射断层扫描才能发现。一名50岁的左利手男性头部和颈部右侧受到轻微创伤。在20分钟内,他出现了右侧面部、前臂、手部和足部的阵发性间歇性肌张力障碍姿势,左脚收缩较弱,持续数秒,每隔几分钟复发一次。发作间期的神经系统检查结果正常。以下各项也均正常:电解质、钙、镁和动脉血气水平,药物筛查、脑脊液检查、鼻咽导联脑电图、计算机断层扫描(初始及四周后)以及脑血管造影的结果。正电子发射断层扫描显示左侧基底神经节区域存在异常,包括氧代谢降低、氧摄取减少、血容量增加和血流增加。

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