Jenness R, Birney E C, Ayaz K L, Buzzell D M
Comp Biochem Physiol B. 1984;78(1):167-73. doi: 10.1016/0305-0491(84)90162-7.
Activity of L-gulonolactone oxidase (EC 1.1.3.8) in livers of fetal Rattus norvegicus and Mus musculus was detectable on the 18th day of gestation, increased rapidly to maxima at 15 and 5 days postpartum for the two species, respectively, and thereafter declined to adult levels. L-Gulonolactone oxidase was not detectable in liver or kidney of fetal guinea pigs at any stage of development. Near-term fetal snowshoe hares had higher activities of liver L-gulonolactone oxidase than observed in a large sample of adults. L-Gulonolactone oxidase was detectable in chicken (Gallus gallus) embryos by the sixth day of incubation, increased rapidly in the kidney with no discontinuity at hatching, reached a maximum at about the 35th day from the beginning of incubation, and then declined to adult levels. Barn swallow (Hirundo rustica) embryos appeared to synthesize little if any L-ascorbic acid; nestlings had considerably higher levels of L-gulonolactone oxidase than adults. Tadpoles of three species of frogs had appreciable levels of L-gulonolactone oxidase activity.
在妊娠第18天可检测到胎生褐家鼠和小家鼠肝脏中L-古洛糖酸内酯氧化酶（EC 1.1.3.8）的活性，这两个物种分别在产后15天和5天迅速增加至最大值，此后下降至成年水平。在豚鼠胎儿发育的任何阶段，其肝脏或肾脏中均未检测到L-古洛糖酸内酯氧化酶。接近足月的胎生雪兔肝脏L-古洛糖酸内酯氧化酶的活性高于大量成年雪兔样本中的观察值。在鸡（原鸡）胚胎孵化的第6天可检测到L-古洛糖酸内酯氧化酶，其在肾脏中迅速增加，孵化时无间断，在孵化开始约第35天达到最大值，然后下降至成年水平。家燕（家燕）胚胎似乎很少合成L-抗坏血酸；雏鸟的L-古洛糖酸内酯氧化酶水平明显高于成鸟。三种青蛙的蝌蚪具有相当水平的L-古洛糖酸内酯氧化酶活性。
