抑郁症患者的血小板单胺氧化酶活性与地塞米松抑制试验

Platelet MAO activity and the dexamethasone suppression test in depressed patients.

作者信息

Schatzberg A F, Orsulak P J, Rothschild A J, Salomon M S, Lerbinger J, Kizuka P P, Cole J O, Schildkraut J J

出版信息

Am J Psychiatry. 1983 Sep;140(9):1231-3. doi: 10.1176/ajp.140.9.1231.

DOI:10.1176/ajp.140.9.1231

Abstract

Platelet monoamine oxidase (MAO) activity and postdexamethasone cortisol levels were determined in 26 depressed patients. The incidence of cortisol nonsuppression and the mean postdexamethasone cortisol levels were significantly higher in patients with high MAO activity than in those with low MAO activity.

摘要

对26名抑郁症患者测定了血小板单胺氧化酶（MAO）活性和地塞米松后的皮质醇水平。MAO活性高的患者中皮质醇不被抑制的发生率和地塞米松后皮质醇平均水平显著高于MAO活性低的患者。