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Toward a biochemical classification of depressive disorders IX. DST results and platelet MAO activity.

作者信息

Schatzberg A F, Rothschild A J, Gerson B, Lerbinger J E, Schildkraut J J

出版信息

Br J Psychiatry. 1985 Jun;146:633-7. doi: 10.1192/bjp.146.6.633.

Abstract

Post-dexamethasone cortisol and platelet monoamine oxidase (MAO) activity levels were examined in 50 depressed patients. The incidence of non-suppression was significantly greater in patients with high platelet MAO activity than in those with low activity. Similar results were obtained when males and females were analysed separately. The mean 4 p.m. post-dexamethasone cortisol level was significantly higher in those patients who had high MAO activity than in their low MAO counterparts. Moreover, a statistically significant positive correlation was observed between platelet MAO activity and 4 p.m. post-dexamethasone cortisol levels.

摘要

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