Webb A R, Lari J, Dodge J A
Arch Dis Child. 1983 Aug;58(8):586-90. doi: 10.1136/adc.58.8.586.
In a retrospective analysis of cases of surgically confirmed infantile hypertrophic pyloric stenosis (IHPS) in South Glamorgan in the decade 1970-9 the incidence rose sharply in 1976 reflecting a general increase reported throughout Wales and from other parts of the United Kingdom. The increase was mainly among boys and although it occurred at a time when breast feeding had become more popular, it affected bottle fed infants more than breast fed infants. The apparent correlation between incidence of IHPS and incidence of breast feeding may coincidental and changes in infant milk formulae that became general in 1976 may be more important. An appreciable excess of first born infants with IHPS was noted but there was no correlation between birthweight and IHPS. Variations according to month of birth did not coincide with true seasonal variation.
在对1970 - 1979年十年间南格拉摩根郡手术确诊的婴儿肥厚性幽门狭窄(IHPS)病例进行的回顾性分析中,1976年发病率急剧上升,这反映了威尔士各地以及英国其他地区报告的普遍上升情况。这种上升主要发生在男孩中,尽管它发生在母乳喂养变得更普遍的时期,但人工喂养的婴儿比母乳喂养的婴儿受影响更大。IHPS发病率与母乳喂养率之间的明显关联可能是巧合,1976年普遍使用的婴儿配方奶粉的变化可能更重要。值得注意的是,患有IHPS的头胎婴儿明显过多,但出生体重与IHPS之间没有关联。根据出生月份的变化与真正的季节变化并不一致。