五肽胃泌素诱导幽门肥大。婴儿肥厚性幽门狭窄的动物模型。
Induction of pyloric hypertrophy by pentagastrin. An animal model for infantile hypertrophic pyloric stenosis.
作者信息
Dodge J A, Karim A A
出版信息
Gut. 1976 Apr;17(4):280-4. doi: 10.1136/gut.17.4.280.
Abstract
Administration of pentagastrin in depot form to 20 pregnant bitches produced pyloric hypertrophy in about 28% and gastroduodenal ulceration in about 16% of their pups. The two lesions were not necessarily found in the same individuals. Histological appearances of the pylorus in affected pups closely resembled those of human infantile pyloric stenosis.
摘要
给20只怀孕母犬注射长效五肽胃泌素后，约28%的幼犬出现幽门肥大，约16%的幼犬出现胃十二指肠溃疡。这两种病变不一定出现在同一幼犬身上。患病幼犬幽门的组织学表现与人类婴儿幽门狭窄的表现极为相似。
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