Kaneoka T, Taguchi S, Shimizu H, Shirakawa K
J Perinat Med. 1983;11(4):204-12. doi: 10.1515/jpme.1983.11.4.204.
Prenatal treatment consisting of daytime bedrest, high protein diet and oral administration of allylestrenol was assessed in a prospective study of 30 patients with IUGR infants whose ultrasonically estimated body weight was less than the 10th percentile. In these pregnancies, the gestational age was confirmed in the first trimester, and the fetal weight was estimated from the BPD and AC measurements in the third trimester (Fig. 1). Following treatment, ultrasonic and biochemical determinations were performed. As results: The estimated fetal weight of 1,362 g at 32.9 g gestational weeks increased to 2,678 g at 39.2 weeks on average. The average weekly weight gain was significantly higher than the standard, and 16 cases (53.3%) were more than 10th percentile at birth (Tab. I, Fig. 2). A significant correlation (r = 0.94) between the estimated fetal weight and the birth weight was found. Following prenatal treatments, maternal plasma and urinary estriol, plasma HPL and progesterone increased significantly (Tab. II).
在一项前瞻性研究中，对30例超声估计体重低于第10百分位数的宫内生长受限（IUGR）婴儿的患者进行了评估，其产前治疗包括日间卧床休息、高蛋白饮食和口服烯丙雌醇。在这些妊娠中，孕早期确定孕周，孕晚期根据双顶径（BPD）和腹围（AC）测量估计胎儿体重（图1）。治疗后，进行了超声和生化测定。结果如下：孕32.9周时估计胎儿体重为1362克，至孕39.2周时平均增至2678克。平均每周体重增加显著高于标准，16例（53.3%）出生时超过第10百分位数（表I，图2）。发现估计胎儿体重与出生体重之间存在显著相关性（r = 0.94）。产前治疗后，母体血浆和尿雌三醇、血浆人胎盘催乳素（HPL）和孕酮显著增加（表II）。
