Acevedo M, Jiménez E, Díez de los Ríos A
Rev Esp Fisiol. 1983 Jun;39(2):123-7.
Sodium, potassium and chloride intracellular concentrations were measured. Sodium replacement from the bathing medium induced a significant decrease in chloride intracellular concentration. Conversely, chloride replacement from the bathing medium induced a significant decrease in sodium intracellular concentration. These results suggest the existence of a coupled NaCl transport system. The presence of 10(-3) M ouabain in the bathing medium increased Na+ intracellular concentration while decreasing that of K+. Cyanide (10(-3) M) produced a significant increase in Na+ intracellular concentration, whereas that of K+ was not affected by this agent.
测量了细胞内钠、钾和氯的浓度。用浴液中的钠替代物会导致细胞内氯浓度显著降低。相反,用浴液中的氯替代物会导致细胞内钠浓度显著降低。这些结果表明存在一种耦合的氯化钠转运系统。浴液中存在10(-3)M哇巴因会增加细胞内Na+浓度,同时降低K+浓度。氰化物(10(-3)M)会使细胞内Na+浓度显著增加,而K+浓度不受该试剂影响。