Shahbabian S, Keller J T, Gould H J, Dunsker S B, Mayfield F H
Surg Neurol. 1983 Oct;20(4):310-2. doi: 10.1016/0090-3019(83)90086-1.
A new technique is described that minimizes the damage to neural tissues caused by the cortical incisions that must be made when operating on intracerebral or intraventricular lesions. Symmetric cortical incisions were made bilaterally in the same region of the middle suprasylvian gyrus in six dogs. Blunt dissection was performed on the right side. A new technique, which utilizes a balloon catheter, was employed on the left side. A greater hemiparesis was observed on the left side in all dogs. There was a mild but definite hemiparesis on the right side in four dogs, which improved within 2-3 days postoperatively. The dogs were killed on the sixth postoperative day. The Fink-Heimer technique for selective staining of degenerating axons and their terminal boutons was used to determine the extent of neuronal damage. Histologic studies support clinical observations in the experimental animal that the neural damage resulting from cortical incision is significantly decreased when the balloon catheter technique is applied.
本文描述了一种新技术，该技术可将在进行脑内或脑室内病变手术时必须进行的皮质切口对神经组织造成的损伤降至最低。在六只狗的中颞上回同一区域双侧进行对称皮质切口。右侧进行钝性分离。左侧采用一种利用球囊导管的新技术。所有狗的左侧均观察到更严重的偏瘫。四只狗的右侧有轻度但明确的偏瘫，术后2 - 3天内有所改善。术后第六天处死这些狗。采用芬克 - 海默技术对变性轴突及其终末小体进行选择性染色，以确定神经元损伤的程度。组织学研究支持实验动物的临床观察结果，即应用球囊导管技术时，皮质切口导致的神经损伤显著减少。
