Sauerbruch T, Stellaard F, Paumgartner G
Digestion. 1983;27(2):87-92. doi: 10.1159/000198935.
The effect of endoscopic sphincterotomy on bile acid pool size and lipid composition was studied in 3 patients with an intact gallbladder and in 7 patients who had previous cholecystectomy. Measurements were made at two time intervals after endoscopic sphincterotomy, early (3-9 days) and late (6-9 months). Patients with an intact gallbladder showed a marked reduction in their total bile acid pool during follow-up examinations (95.3 +/- SD 14.0 vs. 18.6 +/- 8.1 mumol/kg), whereas in the cholecystectomized patients the pool size showed no significant change (29.4 +/- 13.4 vs. 26.6 +/- 11.4 mumol/kg). The reduction in bile acid pool size caused by sphincterotomy in patients with an intact gallbladder did not increase the degree of cholesterol saturation in hepatic bile.
在3例胆囊完整的患者和7例曾行胆囊切除术的患者中，研究了内镜下括约肌切开术对胆汁酸池大小和脂质成分的影响。在内镜下括约肌切开术后的两个时间间隔进行测量，早期（3 - 9天）和晚期（6 - 9个月）。胆囊完整的患者在随访检查期间其总胆汁酸池显著减少（95.3±标准差14.0对18.6±8.1μmol/kg），而在胆囊切除术后的患者中，胆汁酸池大小无显著变化（29.4±13.4对26.6±11.4μmol/kg）。胆囊完整的患者因括约肌切开术导致的胆汁酸池大小减少并未增加肝胆汁中胆固醇饱和程度。
