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用低剂量和高剂量犬钩虫致敏的肠系膜淋巴结细胞转移后受体的免疫反应模式

Pattern of immune response in recipients after transfer of mesenteric lymph node cells sensitized with low and high doses of Ancylostoma caninum.

作者信息

Vardhani V V, Johri G N

出版信息

Folia Parasitol (Praha). 1983;30(3):285-8.

PMID:6629209
Abstract

Cellular immune response was detected in female Swiss albino mice with mesenteric lymph node cells during Ancylostoma caninum infection. Sensitized lymphocytes responded vigorously to A. caninum antigens and it was found that the cells (singly or repeatedly) sensitized with either low or high doses could confer adoptive protective immunity in recipients later challenged with a single dose of 500 A. caninum larvae.

摘要

在犬钩虫感染期间,利用肠系膜淋巴结细胞检测了雌性瑞士白化小鼠的细胞免疫反应。致敏淋巴细胞对犬钩虫抗原反应强烈,并且发现用低剂量或高剂量(单次或反复)致敏的细胞能够使受体在随后用500条犬钩虫幼虫单剂量攻击时获得过继性保护性免疫。

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