Khare C B, Sankaranarayanan A, Goel A, Khandelwal S K, Srinivasa Murthy R
Int J Clin Pharmacol Ther Toxicol. 1983 Sep;21(9):451-3.
The usefulness of salivary lithium values for monitoring long-term lithium prophylaxis was studied in 60 patients on lithium therapy. A total of 99 pairs of saliva and serum samples were obtained, and the correlation between serum and salivary lithium levels (r = 0.73) was found to be significant at the 1% level. The ratio of salivary serum levels to that of serum was found to range from 1.77 to 6.68. The ratio of 51% of the samples was between 3 and 3.99. It is therefore suggested that it is important to identify the subgroup of patients who show better correlation of salivary and serum lithium levels and use each individual's ratio to monitor only his lithium therapy.
对60名接受锂盐治疗的患者进行了研究，以探讨唾液锂值在监测长期锂盐预防性治疗中的作用。共采集了99对唾液和血清样本，发现血清和唾液锂水平之间的相关性（r = 0.73）在1%水平上具有显著性。唾液与血清锂水平的比值在1.77至6.68之间。51%的样本比值在3至3.99之间。因此，建议识别出唾液和血清锂水平相关性更好的患者亚组，并使用每个个体的比值来单独监测其锂盐治疗，这一点很重要。
