唾液锂浓度——一种监测精神科患者的工具。

Salivary lithium concentration--a tool for monitoring psychiatric patients.

作者信息

Ben-Aryeh H, Naon H, Szargel R, Gutman D, Hefetz A

出版信息

Oral Surg Oral Med Oral Pathol. 1980 Aug;50(2):127-9. doi: 10.1016/0030-4220(80)90198-x.

Abstract

Salivary and serum lithium concentrations were measured simultaneously in 118 manic-depressive patients. Lithium concentration in saliva was 2.24 +/- 0.35 times higher than in serum. An equation to calculate serum lithium concentration from salivary measurements was derived: Li serum = 0.36 Li saliva + 0.13. Psychotropic drugs had no effect on the salivary:serum ratio. Eighteen patients were followed for several weeks. A significant correlation coefficient between salivary and serum lithium concentrations was found in thirteen of the eighteen patients studied.

摘要

对118名躁郁症患者同时测量了唾液和血清中的锂浓度。唾液中的锂浓度比血清中的高2.24±0.35倍。推导出一个根据唾液测量值计算血清锂浓度的公式：血清锂浓度 = 0.36×唾液锂浓度 + 0.13。精神药物对唾液与血清的比例没有影响。对18名患者进行了数周的跟踪。在研究的18名患者中，有13名患者的唾液和血清锂浓度之间存在显著的相关系数。