Neinstein L S, Stewart D, Wang C I, Johnson I
J Adolesc Health Care. 1983 Sep;4(3):153-7. doi: 10.1016/s0197-0070(83)80367-2.
Several factors potentially involved in the menstrual dysfunction of some females with cystic fibrosis were analyzed by a retrospective chart review. The mean age of menarche for the cystic fibrosis patients was 14.4 years, compared to 12.9 years for American females (p less than 0.001). At last evaluation, comparison of the mean figures for amenorrheic patients and for menarchal cystic fibrosis patients reveals statistically significant differences in the age of diagnosis, weight-height index, weight, height, percent of body fat, weight percentile, and height percentile. The highest correlative was weight (r = 0.59). Of our cystic fibrosis patients who were menarchal, 95% had a weight greater than 82 pounds, whereas 75% of those who were amenorrheic weighed less than 82 pounds. Menstrual irregularities, sexual activity, and contraceptive use among these patients also is discussed.
通过回顾性病历审查分析了一些患有囊性纤维化的女性月经功能障碍可能涉及的几个因素。囊性纤维化患者的初潮平均年龄为14.4岁，而美国女性为12.9岁（p<0.001）。在最后一次评估中，闭经患者和初潮囊性纤维化患者的平均数据比较显示，在诊断年龄、体重身高指数、体重、身高、体脂百分比、体重百分位数和身高百分位数方面存在统计学上的显著差异。相关性最高的是体重（r=0.59）。在我们有初潮的囊性纤维化患者中，95%的人体重超过82磅，而闭经患者中有75%的人体重低于82磅。还讨论了这些患者的月经不规律、性活动和避孕措施的使用情况。
