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裂脑患者对双侧半球刺激的统一反应。

Unified response to bilateral hemispheric stimulation by a split-brain patient.

作者信息

Sergent J

出版信息

Nature. 1983;305(5937):800-2. doi: 10.1038/305800a0.

DOI:10.1038/305800a0
PMID:6633650
Abstract

Surgical sectioning of the corpus callosum in epileptic patients has provided a unique opportunity to study separately the competence and processing capacities of the two cerebral hemispheres, each of which is able to perceive, think, memorize and learn independently and essentially outside the realm of awareness of the other. While research has focused on this 'disconnection syndrome', split-brain patients nonetheless behave as unified individuals in their normal environment, and the present study investigated this aspect of their behaviour in an experimental setting. The two hemispheres of a callosotomized patient were simultaneously presented with information associated with conflicting responses, and the subject was requested to produce a single response. In all combinations of hemisphere stimulation and hand responding, the subject was capable of perfect accuracy, suggesting that he could integrate and resolve the conflicting information before the production of his response, and that his two disconnected hemispheres were simultaneously aiming at the same goal.

摘要

对癫痫患者进行胼胝体切开手术,为分别研究两个脑半球的能力和处理能力提供了独特的机会,每个脑半球都能够独立地感知、思考、记忆和学习,而且基本上是在彼此的意识范围之外进行的。虽然研究集中在这种“分离综合征”上,但裂脑患者在正常环境中仍表现得像一个统一的个体,本研究在实验环境中调查了他们行为的这一方面。同时向胼胝体切开患者的两个脑半球呈现与冲突反应相关的信息,并要求受试者做出单一反应。在脑半球刺激和手部反应的所有组合中,受试者都能达到完美的准确性,这表明他能够在做出反应之前整合并解决冲突信息,而且他的两个分离的脑半球同时朝着同一个目标。

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The role of the corpus callosum in interhemispheric transfer of information: excitation or inhibition?胼胝体在半球间信息传递中的作用:兴奋还是抑制?
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