Kennedy L A, Persaud T V
Res Commun Chem Pathol Pharmacol. 1978 Apr;20(1):179-82.
Pregnant rats were treated intraperitoneally with low doses of pentobarbital (5, 15 or 25 mg/kg) on days 9 through 12 of gestation. There was no significant differences in fetal weight, length, or placental weight. Other than minor ossification delays, there were no external, skeletal or visceral abnormalities and no treatment-related variation in fetal mortality. Microscopic examination of various maternal and fetal tissues revealed no major deleterious effects of short-term pentobarbital intoxication.
在妊娠第9至12天，给怀孕大鼠腹腔注射低剂量戊巴比妥（5、15或25毫克/千克）。胎儿体重、长度或胎盘重量没有显著差异。除了轻微的骨化延迟外，没有外部、骨骼或内脏异常，胎儿死亡率也没有与治疗相关的变化。对各种母体和胎儿组织的显微镜检查显示，短期戊巴比妥中毒没有重大有害影响。
