在上丘单侧注射GABA激动剂：对触觉刺激的不对称性。
Unilateral injection of GABA agonists in the superior colliculus: asymmetry to tactile stimulation.
作者信息
Di Scala G, Schmitt P, Karli P
出版信息
Pharmacol Biochem Behav. 1983 Aug;19(2):281-5. doi: 10.1016/0091-3057(83)90053-9.
A unilateral microinjection of each one of three different GABA agonists (Muscimol: 1.4 nmoles; Baclofen: 0.8 nmole; THIP: 10.7 nmoles) into the superior colliculus was found to result in a reversible asymmetry in the rat's responsiveness to tactile stimulation. The rat was hyporeactive to stimulations applied contralaterally and hyperreactive to stimulations applied ipsilaterally to the infusion site. Furthermore, the rat showed ipsiversive turning in response to tactile stimulation applied either ipsi- or contralaterally to the infusion site. The results are discussed in relation with motor and sensory asymmetry produced by unilateral manipulations affecting the striato-nigro tectal system.
向大鼠上丘单侧微量注射三种不同的GABA激动剂（蝇蕈醇：1.4纳摩尔；巴氯芬：0.8纳摩尔；4,5,6,7-四氢异喹啉-3-醇：10.7纳摩尔）中的每一种，结果发现会导致大鼠对触觉刺激的反应出现可逆性不对称。大鼠对注射部位对侧施加的刺激反应减弱，而对同侧施加的刺激反应增强。此外，大鼠在对注射部位同侧或对侧施加触觉刺激时会出现向同侧旋转。本文结合影响纹状体-黑质-顶盖系统的单侧操作所产生的运动和感觉不对称来讨论这些结果。
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