von Arbin M, Britton M, de Faire U, Gustafsson P
Scand J Clin Lab Invest. 1983 Jun;43(4):275-83.
The internal carotid arteries were evaluated with Doppler ultrasound technique in patients with acute cerebrovascular disease. The results of the Doppler examination of 325 vessels were compared to presence of carotid bruits on auscultation. In 126 arteries the findings were also compared with those on aortocervical, single carotid or post-mortal angiography. The Doppler flow reaction was normal in 74% of the vessels, uncertain in 20% and pathologic in 6%. The sensitivity of the Doppler assessment in finding stenosis of more than 75% lumen diameter reduction was 85% with a specificity of 94%. The specificity increased with higher degree of vascular stenosis. Carotid bruits were heard in 34 arteries. The sensitivity of auscultation in detecting stenosis 75% was 47% with a specificity of 83%. The sensitivity fell with higher degree of stenosis. The Doppler procedure is a valuable tool in detecting haemodynamically significant stenoses in the internal carotid artery. The method could serve the following purposes in the clinical situation: 1. Screening procedure for further investigations in TIA and minor stroke patients fit enough to be candidates for vascular surgery. 2. Before blood-pressure can be safely reduced in patients with cerebrovascular disease. 3. For evaluation of the arteriosclerotic process in stroke-patients thereby improving prognostication.
采用多普勒超声技术对急性脑血管疾病患者的颈内动脉进行评估。将325条血管的多普勒检查结果与听诊时颈动脉杂音的存在情况进行比较。对其中126条动脉的检查结果还与主动脉颈段、单条颈动脉造影或尸检血管造影结果进行了比较。74%的血管多普勒血流反应正常，20%不确定，6%为病理性。多普勒评估发现管腔直径缩小超过75%狭窄的敏感性为85%，特异性为94%。特异性随血管狭窄程度的增加而升高。在34条动脉中听到了颈动脉杂音。听诊检测75%狭窄的敏感性为47%，特异性为83%。敏感性随狭窄程度的增加而降低。多普勒检查是检测颈内动脉血流动力学显著狭窄的一项有价值的工具。该方法在临床情况下可用于以下目的：1. 作为对适合血管手术的短暂性脑缺血发作（TIA）和轻度中风患者进行进一步检查的筛查程序。2. 在脑血管疾病患者血压能够安全降低之前。3. 用于评估中风患者的动脉硬化过程，从而改善预后。
