使用速尿治疗的急性心源性肺水肿患者的血液粘度变化

Variations in blood viscosity in patients with acute cardiogenic pulmonary oedema treated with frusemide.

作者信息

Jahnsen T, Skovborg F, Hansen F, Larsen J, Nordin H, Storm T

出版信息

Scand J Clin Lab Invest. 1983 Jun;43(4):297-300.

Abstract

In 10 patients with acute cardiogenic pulmonary oedema, treatment with large doses of intravenous frusemide (mean dose 156 mg) induced no signs of haemoconcentration. On the contrary, during an observation period of 2 h after start of treatment we registered a significant reduction of mean blood viscosity and mean haematocrit, indicating haemodilution. All the patients also received a basic treatment of intravenous pethidine and nasal oxygen and the conclusion is therefore that large doses of intravenous frusemide in treatment of acute cardiogenic pulmonary oedema can be given without risk of haemoconcentration when combined with intravenous pethidine and nasal oxygen.

摘要

在10例急性心源性肺水肿患者中，大剂量静脉注射速尿（平均剂量156毫克）治疗未引起血液浓缩迹象。相反，在治疗开始后的2小时观察期内，我们记录到平均血液粘度和平均血细胞比容显著降低，表明出现了血液稀释。所有患者还接受了静脉注射哌替啶和鼻导管给氧的基础治疗，因此得出结论：在联合静脉注射哌替啶和鼻导管给氧时，大剂量静脉注射速尿治疗急性心源性肺水肿不会有血液浓缩的风险。