Levin L G, Gapparov M M
Vopr Pitan. 1983 Sep-Oct(5):21-3.
A study was made of the effect of high-fatty and high-carbohydrate diets on the rate of the renewal of individual rat myocardial proteins, particularly on the half-life and the constant of degradation of proteins of sarcoplasm, myosin and actin. Unlike the control diet, the high-carbohydrate diet increased the rate of myosin renewal by 25%, while the fatty diet retarded 20% the rate of the renewal of the main contractile myocardial protein. Similar changes were also found for proteins of sarcoplasma: with the high-carbohydrate diet the rate of the renewal increased 10%, whereas with the high-fatty one it diminished 47%. The rate of actin renewal dropped 11% with the high-carbohydrate diet and 30% with the high-fatty diet. Unbalance in carbohydrate and fatty supply of the body produces appreciable changes in the rate of the renewal of individual proteins of the rat myocardium.
研究了高脂和高碳水化合物饮食对大鼠个体心肌蛋白更新率的影响，特别是对肌浆、肌球蛋白和肌动蛋白的半衰期和降解常数的影响。与对照饮食不同，高碳水化合物饮食使肌球蛋白更新率提高了25%，而高脂肪饮食使心肌主要收缩蛋白的更新率降低了20%。肌浆蛋白也发现了类似变化：高碳水化合物饮食时更新率提高了10%，而高脂肪饮食时则降低了47%。高碳水化合物饮食时肌动蛋白更新率下降了11%，高脂肪饮食时下降了30%。机体碳水化合物和脂肪供应失衡会使大鼠心肌单个蛋白质的更新率产生明显变化。
