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卡介苗作为免疫刺激剂在肺癌外科治疗中的应用:五年随访报告。

Use of BCG as an immunostimulant in the surgical treatment of carcinoma of lung: a five-year follow-up report.

作者信息

Edwards F R, Whitwell F

出版信息

Thorax. 1978 Apr;33(2):250-2. doi: 10.1136/thx.33.2.250.

DOI:10.1136/thx.33.2.250
PMID:663885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC470878/
Abstract

Sixty consecutive surviving patients treated with subdermal BCG (5 X 10(6) organisms) have been followed up for five years after resection of lung carcinoma. A control group of the previous 60 consecutive surviving patients not treated with BCG was similarly studied. We found no statistical evidence that the administration of BCG by the method described influenced the five-year survival rate, nor has any effective action upon involved lymph nodes or small metastases been demonstrated.

摘要

连续60例接受皮下注射卡介苗(5×10⁶个菌体)治疗的肺癌切除术后存活患者已被随访五年。对之前连续60例未接受卡介苗治疗的存活患者组成的对照组进行了类似研究。我们没有发现统计学证据表明按所述方法给予卡介苗会影响五年生存率,也未证明其对受累淋巴结或微小转移灶有任何有效作用。

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Use of BCG as an immunostimulant in the surgical treatment of carcinoma of lung: a five-year follow-up report.卡介苗作为免疫刺激剂在肺癌外科治疗中的应用:五年随访报告。
Thorax. 1978 Apr;33(2):250-2. doi: 10.1136/thx.33.2.250.
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Use of BCG as an immunostimulant in the surgical treatment of carcinoma of the lung.卡介苗作为免疫刺激剂在肺癌手术治疗中的应用。
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引用本文的文献

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Thorax. 1982 Aug;37(8):588-93. doi: 10.1136/thx.37.8.588.
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3
Specific and nonspecific immunotherapy as an adjunct to curative surgery for cancer of the lung.特异性和非特异性免疫疗法作为肺癌根治性手术的辅助治疗手段。
Yale J Biol Med. 1981 Sep-Oct;54(5):367-79.
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J Cancer Res Clin Oncol. 1985;109(1):72-7. doi: 10.1007/BF01884258.
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The endogenous induction of tumor necrosis factor serum (TNS) for the adjuvant postoperative immunotherapy of cancer--changes in immunological markers of the blood.用于癌症术后辅助免疫治疗的肿瘤坏死因子血清(TNS)内源性诱导——血液免疫标志物的变化
Jpn J Surg. 1990 Jan;20(1):19-26. doi: 10.1007/BF02470709.
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Cell-mediated immunity in operable bronchial carcinoma: the effect of injecting irradiated autologous tumour cells and BCG.可手术支气管癌的细胞介导免疫:注射经照射的自体肿瘤细胞和卡介苗的效果
Thorax. 1979 Feb;34(1):68-73. doi: 10.1136/thx.34.1.68.
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本文引用的文献

1
Use of BCG as an immunostimulant in the surgical treatment of carcinoma of the lung.卡介苗作为免疫刺激剂在肺癌手术治疗中的应用。
Thorax. 1974 Nov;29(6):654-8. doi: 10.1136/thx.29.6.654.