Negre J B
Ann Surg. 1983 Dec;198(6):698-700. doi: 10.1097/00000658-198312000-00005.
The post-fundoplication symptoms were assessed in 226 patients who had symptomatical improvement of gastroesophageal reflux after Nissen fundoplication. Follow-up range was from 3 to 12 years (average 5,6 years). Of these patients, 24% were totally asymptomatic. All had transient postoperative dysphagia which improved within an average of 3-5 months. Forty four per cent had changes in habits of swallowing; 38% had increased abdominal meteorism; 31% were unable to vomit and 19% unable to belch; 12% had pain in the upper left abdominal quadrant; and 10% had dyspepsia. These symptoms were uncomfortable in 26% and disturbing in 10%. Diverse causes can be responsible for these symptoms; mechanical (narrowing of the cardia, postoperative adherences), functional (motor troubles, denervation), and depending of the patients (alimentary habits). The high frequency of post-fundoplication symptoms restrict clearly the success of Nissen fundoplication.
对226例在进行nissen胃底折叠术后胃食管反流症状得到改善的患者进行了胃底折叠术后症状评估。随访时间为3至12年(平均5.6年)。在这些患者中,24%完全无症状。所有人术后均有短暂性吞咽困难,平均在3至5个月内改善。44%的患者吞咽习惯改变;38%的患者腹胀增加;31%的患者无法呕吐,19%的患者无法嗳气;12%的患者左上腹疼痛;10%的患者有消化不良。这些症状在26%的患者中令人不适,在10%的患者中造成困扰。多种原因可导致这些症状;机械性原因(贲门狭窄、术后粘连)、功能性原因(运动障碍、去神经支配)以及取决于患者自身的原因(饮食习惯)。胃底折叠术后症状的高发生率明显限制了nissen胃底折叠术的成功率。