Williams D F, Gore L F, Clark G C
Biomaterials. 1983 Oct;4(4):285-8. doi: 10.1016/0142-9612(83)90029-7.
Stainless steel (elastic modulus 210 GN/m2) and carbon fibre reinforced epoxy resin (elastic modulus 65 GN/m2) plates have been attached to intact femora in cats and the development of disuse osteoporosis assessed by microdensitometric methods after 8 months. The bone adjacent to the stainless steel plate showed evidence of considerable demineralization, both uniformly throughout a section and especially at certain focal points. A noticeable, but much smaller amount of osteoporosis developed adjacent to the composite plate. Various methods of presenting quantitative micro-densitometric data are used.
