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Phase II clinical trial of L-alanosine in advanced upper aerodigestive cancer.

作者信息

Creagan E T, Schutt A J, Ingle J N, O'Fallon J R

出版信息

Cancer Treat Rep. 1983 Nov;67(11):1047.

PMID:6640554
Abstract
摘要

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A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer.一项关于L-丙氨酸(一种腺嘌呤生物合成的强效抑制剂)在MTAP缺陷型癌症患者中的II期多中心研究。
Invest New Drugs. 2009 Feb;27(1):75-81. doi: 10.1007/s10637-008-9160-1. Epub 2008 Jul 11.
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Phase II study of L-alanosine (NSC 153353) in patients with advanced breast cancer. A Southwest Oncology Group study.
Invest New Drugs. 1991 Feb;9(1):87-8. doi: 10.1007/BF00194553.