de Moura R S, Rozental R
Exp Parasitol. 1983 Dec;56(3):314-7. doi: 10.1016/0014-4894(83)90076-0.
A new method for recording the motility of Schistosoma mansoni in vitro is described. Spontaneous activity of the worm shows contraction similar to peristalsis. The worm responded to electrical stimulation with an immediate contraction that was voltage dependent. Oxamniquine produced an increase in the tonus and spontaneous activity of the worm. This method provides a new experimental model for the study of drugs that interfere with Schistosoma mansoni motility.
本文描述了一种记录曼氏血吸虫体外运动能力的新方法。虫体的自发活动表现出类似于蠕动的收缩。虫体对电刺激产生即时收缩反应,且这种反应依赖于电压。奥沙尼喹使虫体的紧张度和自发活动增加。该方法为研究干扰曼氏血吸虫运动能力的药物提供了一种新的实验模型。