[Effect of hypothalamic stimulation on lactate- and malate dehydrogenase activities in rat cardiac muscle].

The activity of lactic and malic dehydrogenases was examined in the rat heart after stimulation of the hypothalamus. The activity of LDG and MDG was increased after stimulation of the paraventricular nuclei of the hypothalamus and decreased after stimulation of the ventromedial nuclei. Both effects were abolished by preliminary injection of actinomycin D. This finding suggests an important role of heart cells' genetic apparatus in the neurohormonal regulation of the heart metabolism.