Vecchio C, Griffo R, La Rovere M T, Gigli Berzolari F
G Ital Cardiol. 1983 Jul;13(7):3-10.
A maximal, symptom-limited exercise test was performed 4 weeks after an acute myocardial infarction in 108 subjects aged less than 40. All the patients were afterwards engaged in a 6 weeks supervised rehabilitation program. Following the rehabilitation, 99 patients underwent programmed controls for a mean period of 23.4 +/- 16 months. Anamnestic data, site of the infarction, early exercise test response, rehabilitation results were statistically evaluated. They were compared with the follow-up data to estimate their predictive value of late cardiac events. Only the exercise testing data were found to be of prognostic significance. In fact, 77.8% of patients with ischemic response to the test had new cardiac events in the follow-up period. The percentage of late cardiac events was 26.7% in patients with hypotensive response and 8.4% in patients with normal response. The ischemic response was found to be more frequent in patients with inferior myocardial infarction. The highest rate of new cardiac events (86%) occurred in patients with inferior infarction and ischemic response to the early exercise test. An early exercise test seems to be of value to assess the prognosis after a myocardial infarction in young men. An ischemic response is a reliable sign of a poor prognosis; on the other hand, a normal response to the test does not exclude the possibility of late cardiac events, which may occur in about 10% of these patients.
对108名年龄小于40岁的急性心肌梗死后4周的患者进行了最大症状限制运动试验。所有患者随后参加了为期6周的有监督的康复计划。康复后,99名患者进行了平均为期23.4±16个月的程控。对既往病史、梗死部位、早期运动试验反应、康复结果进行了统计学评估。将它们与随访数据进行比较,以评估其对晚期心脏事件的预测价值。结果发现只有运动试验数据具有预后意义。事实上,试验出现缺血反应的患者中有77.8%在随访期发生了新的心脏事件。低血压反应患者晚期心脏事件的发生率为26.7%,正常反应患者为8.4%。下壁心肌梗死患者缺血反应更为常见。下壁梗死且早期运动试验出现缺血反应的患者新心脏事件发生率最高(86%)。早期运动试验似乎对评估年轻男性心肌梗死后的预后有价值。缺血反应是预后不良的可靠标志;另一方面,试验正常反应并不能排除晚期心脏事件的可能性,约10%的此类患者可能会发生晚期心脏事件。