Ficek W
Gegenbaurs Morphol Jahrb. 1983;129(4):445-58.
The experiments were carried out with the cultured thymic glands of the 7 d old rats. 3H-thymidine incorporation rate, histological alterations and the lipid level within the entire gland were studied. In cultures supplemented with 200 ng of vasopressin per ml of medium, the amount of the incorporated 3H-thymidine was lower than in the control cultures, whereas in cultures to which higher quantities of the same hormone (10 micrograms/ml) were added a reverse effect was observed and the difference was statistically significant as compared with the control cultures (p less than 0.001). Addition of oxytocin (0.01 units/ml of the medium) to the culture brought about a slight increase in the incorporation of 3H-thymidine. Histological and histochemical studies showed that the involution of the thymic tissue was least pronounced in the cultures supplemented with vasopressin in amount of 10 micrograms per ml of the medium.
实验采用7日龄大鼠的培养胸腺进行。研究了3H-胸腺嘧啶核苷掺入率、组织学改变以及整个腺体中的脂质水平。在每毫升培养基中添加200 ng血管加压素的培养物中，3H-胸腺嘧啶核苷的掺入量低于对照培养物，而在添加了更高量相同激素（10 μg/ml）的培养物中，观察到相反的效果，与对照培养物相比差异具有统计学意义（p<0.001）。向培养物中添加催产素（0.01单位/ml培养基）导致3H-胸腺嘧啶核苷掺入量略有增加。组织学和组织化学研究表明，在每毫升培养基中添加10 μg血管加压素的培养物中，胸腺组织的退化最不明显。
