Schena F P, Manno C, Carabellese S, Dimonte D, Paglionico N, Cazzato L
Int J Artif Organs. 1983 Jul;6 Suppl 1:29-33.
Plasma exchange (PE) was performed in 8 of 14 patients with systemic lupus erythematosus (SLE) PE was instituted as an additional therapy during active disease in patients who did not respond to conventional therapy. The best results were obtained in plasmapherized patients; in fact, immune complex serum levels disappeared rapidly, whereas anti-DNA antibodies decreased slowly. The changes observed indicate that PE may be beneficial, especially when it is associated with drugs that can block antibody rebound. A variety of "technical factors" may influence PE therapy which therefore must be monitored appropriately.
14例系统性红斑狼疮（SLE）患者中有8例接受了血浆置换（PE）治疗。在对传统治疗无反应的患者处于疾病活动期时，将血浆置换作为一种辅助治疗方法。血浆置换患者取得了最佳疗效；事实上，免疫复合物血清水平迅速消失，而抗DNA抗体则缓慢下降。观察到的这些变化表明，血浆置换可能有益，尤其是当它与能够阻止抗体反弹的药物联合使用时。多种“技术因素”可能会影响血浆置换治疗，因此必须对其进行适当监测。
