Menon T J, Thjellesen D, Wroblewski B M
J Bone Joint Surg Br. 1983 Nov;65(5):580-1. doi: 10.1302/0301-620X.65B5.6643560.
A retrospective study of 44 diabetic patients who, between them, had 62 Charnley low-friction arthroplasties, showed a superficial-infection rate of 9.7 per cent and a deep-infection rate of 5.6 per cent. All the operations were carried out in the Charnley clear-air enclosure and prophylactic antibiotics were not used. A statistically significant increase in the overall rate of infection was found in diabetic patients when compared with non-diabetic osteoarthritic patients (P less than 0.001) and rheumatoid patients (P less than 0.01). Hence it is suggested that in diabetic patients there may well be a place for prophylactic antibiotics in hip replacement surgery in addition to the use of the clean-air enclosure.
一项对44名糖尿病患者的回顾性研究显示，他们共接受了62例Charnley低摩擦人工关节置换术，其浅表感染率为9.7%，深部感染率为5.6%。所有手术均在Charnley层流空气净化手术室进行，未使用预防性抗生素。与非糖尿病性骨关节炎患者（P<0.001）和类风湿性关节炎患者（P<0.01）相比，糖尿病患者的总体感染率有统计学意义的显著增加。因此，有人建议，除了使用层流空气净化手术室之外，糖尿病患者在髋关节置换手术中预防性使用抗生素可能很有必要。
