Bronner A K, Hood A F
J Am Acad Dermatol. 1983 Nov;9(5):645-63. doi: 10.1016/s0190-9622(83)70177-5.
Increasing numbers of chemotherapeutic agents are being used to treat patients with cancer and various immunologically mediated and inflammatory disorders. Many of the drugs used have distinctive cutaneous side effects that range from relatively common ones, such as alopecia, stomatitis, and hyperpigmentation, to more unusual ones, such as radiation enhancement and recall phenomena, photosensitivity and hypersensitivity reactions, and phlebitis or chemical cellulitis. In addition, there are some rare complications such as diffuse sclerosis of the hands and feet, Raynaud's phenomenon, sterile folliculitis, and flushing reactions. By being aware of which drug may have caused a particular cutaneous reaction, dermatologists will be able to contribute to the care of patients with complex problems in a meaningful way.
越来越多的化疗药物被用于治疗癌症患者以及各种免疫介导性和炎症性疾病。许多所使用的药物具有独特的皮肤副作用，范围从相对常见的，如脱发、口腔炎和色素沉着，到较不常见的，如放射增强和回忆现象、光敏性和超敏反应，以及静脉炎或化学性蜂窝织炎。此外，还有一些罕见的并发症，如手足弥漫性硬化、雷诺现象、无菌性毛囊炎和潮红反应。通过了解哪种药物可能导致了特定的皮肤反应，皮肤科医生将能够以有意义的方式为患有复杂问题的患者提供护理。
