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[5-羟色胺硫酸肌酐和重酒石酸去甲肾上腺素对体外培养大脑皮质外植体生长影响的形态学研究]

[Morphometric studies on the effect of 5-hydroxytryptamine creatinine sulfate and noradrenaline bitartrate on the growth of cerebral cortex explants in vitro].

作者信息

Goworek K, Pfister C

出版信息

J Hirnforsch. 1983;24(4):357-61.

PMID:6643989
Abstract

Explants of cerebral cortex of neonatal rats were cultivated up to 15 DIV being treated with 5-hydroxytryptamine and noradrenaline, resp. Effects of exogenous transmitters on the growth of explants were investigated by means of morphometrical methods. Different effects on the growth depending on the duration of cultivation and the type of transmitter administered were found. Stimulatory influences have been seen to occur up to 4 DIV (noradrenaline) and up to 2 DIV (serotonin).

摘要

新生大鼠大脑皮层外植体培养至第15天,分别用5-羟色胺和去甲肾上腺素处理。通过形态计量学方法研究了外源性递质对培养外植体生长的影响。发现根据培养时间和所施用递质类型的不同,对生长有不同影响。在培养至第4天(去甲肾上腺素)和第2天(血清素)时观察到有刺激作用。

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