Cloutier R, Fournier L, Levasseur L
J Pediatr Surg. 1983 Oct;18(5):551-4. doi: 10.1016/s0022-3468(83)80357-1.
A review of 26 patients with congenital diaphragmatic hernia, diagnosed in the first 24 hours of life, supports the hypothesis that the postoperative fetal circulation syndrome is an iatrogenic complication, due to the rapid expansion of both lungs, when they are severely hypoplastic. This complication is preventable, when no aspiration of air from the chest cavity is done, and when no tube attached to an underwater seal is inserted. When assisted ventilation is necessary, small volumes at a rapid rate allows satisfactory gaseous exchanges, without pulmonary overinflation.
对26例在出生后24小时内确诊的先天性膈疝患者的回顾支持了以下假设:术后胎儿循环综合征是一种医源性并发症,原因是当两肺严重发育不全时迅速扩张。当不进行胸腔内空气抽吸且不插入连接水下密封装置的导管时,这种并发症是可以预防的。当需要辅助通气时,小潮气量、高频率通气可实现满意的气体交换,而不会导致肺过度膨胀。