Lassaletta L, Ros Z, Queizán A, Benavent M, Cabrera R, Jaureguizar E, Martínez A
An Esp Pediatr. 1980 Aug;13(8):651-6.
During the last ten year period, 78 newborns with congenital diaphragmatic hernia were seen at the Clinica Infantil "La Paz", Madrid. Twenty seven cases died immediately after delivery and 51 were operated. Necropsy findings showed pulmonary hypoplasia and patent ductus arteriosus. Mortality rate in operated cases was 29%. It seems that pulmonary hypoplasia increases pulmonary vascular resistance resulting in a state of fetal circulation with right-to-left shunting through ductus arteriosus. In these cases right to left shunt with umbilical and temporal artery catheters measuring pre and postductal pO2 must be demonstrated. Authors show their experience with two cases of newborns with Bockdalek hernia treated with tolazoline in postoperative period. Both survived.
在过去十年间,马德里的“拉巴斯”儿童医院共收治了78例先天性膈疝新生儿。27例出生后即刻死亡,51例接受了手术治疗。尸检结果显示肺发育不全和动脉导管未闭。手术病例的死亡率为29%。似乎肺发育不全会增加肺血管阻力,导致出现胎儿循环状态,血液通过动脉导管从右向左分流。在这些病例中,必须通过脐动脉和颞动脉导管测量导管前后的血氧分压,以证实存在从右向左的分流。作者介绍了两例波克达勒克疝新生儿术后使用妥拉唑啉治疗的经验。两例均存活。