Tozuka K, Konjiki T, Sudo T
J Urol. 1983 Dec;130(6):1119-22. doi: 10.1016/s0022-5347(17)51713-9.
X-ray powder diffraction, infrared spectroscopy and thermal analysis were used to study 108 stones that had been passed spontaneously from the upper urinary tract. The presence of apatite in pure calcium oxalate stones classified by x-ray diffraction was confirmed by infrared analysis of the ignited product. Consequently, 102 of 108 stones were found to be composed of weddellite and/or whewellite, and apatite. Besides the contents of weddellite, whewellite and apatite, the content of organic matrix also was estimated by thermal analysis in 102 stones, ranging from 1.1 to 17.2 per cent. The stones then were divided into 3 groups according to the principal constituent: 1) weddellite, 2) whewellite and 3) apatite. Weddellite stones were significantly heavier and significantly higher in apatite content than whewellite stones. It is suggested that weddellite calculi tend to become larger than whewellite stones. The apatite content was correlated with the ratio of weddellite to weddellite plus whewellite ( r equals 0.528), and the content of organic matrix was correlated with the whewellite content (r equals 0.708). Thus, it is considered that the weddellite-apatite and whewellite-organic matrix associations have important roles in the development and growth of weddellite and whewellite calculi, respectively.
采用X射线粉末衍射、红外光谱和热分析等方法，对108颗自上尿路自然排出的结石进行了研究。通过对灼烧产物的红外分析，证实了X射线衍射分类的纯草酸钙结石中磷灰石的存在。结果发现，108颗结石中有102颗由水草酸钙和/或二水草酸钙以及磷灰石组成。除了水草酸钙、二水草酸钙和磷灰石的含量外，还通过热分析对102颗结石中的有机基质含量进行了估算，范围为1.1%至17.2%。然后根据主要成分将结石分为3组：1）水草酸钙结石，2）二水草酸钙结石，3）磷灰石结石。水草酸钙结石比二水草酸钙结石明显更重，磷灰石含量也明显更高。提示水草酸钙结石往往比二水草酸钙结石更大。磷灰石含量与水草酸钙与水草酸钙加二水草酸钙的比例相关（r等于0.528），有机基质含量与二水草酸钙含量相关（r等于0.708）。因此，认为水草酸钙-磷灰石和二水草酸钙-有机基质的组合分别在水草酸钙和二水草酸钙结石的形成和生长中起重要作用。
