Thorne P S, Lightfoot E N, Gonder J C, Will J A
Lab Anim Sci. 1983 Oct;33(5):476-80.
A closed-circuit chamber system for exposing animals to toxic concentrations of oxygen or nitrogen was designed and built. The facility was equipped with systems for the removal of carbon dioxide, ammonia, methane, water vapor, and particulates from the gas stream. Integral systems were built to monitor and control temperature (+/- 1 degree C), relative humidity (+/- 2%), oxygen concentration (10 to 100% +/- 0.5%), and methane concentration (below 2%). Operation was set at standard pressure (1.0 X 10(5) Newtons/m2). Hyperoxic studies have been performed on six species of rodents, as well as sheep, and have lasted from 1 to 28 days.
设计并建造了一个用于使动物暴露于有毒浓度氧气或氮气的闭路舱室系统。该设施配备了用于从气流中去除二氧化碳、氨、甲烷、水蒸气和颗粒物的系统。构建了集成系统来监测和控制温度（±1摄氏度）、相对湿度（±2%）、氧气浓度（10%至100%±0.5%）和甲烷浓度（低于2%）。操作设定在标准压力（1.0×10⁵牛顿/平方米）下进行。已对六种啮齿动物以及绵羊进行了高氧研究，研究持续时间为1至28天。
