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[一种用于小动物的简易一氧化氮暴露系统]

[A simple nitric oxide exposure system for small animals].

作者信息

Xiong C, Cheng X, He J, Cui X, Li Z

机构信息

Cardiovascular Institute, PUMC, Beijing.

出版信息

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 1997 Aug;13(3):275-7.

Abstract

A nitric oxide exposing system was designed for experimental research, which consist of equipments such as plexiglass chamber, blower, flowmeter, NO/N2 cylinder, pure O2 cylinder, NOx analyzer, and O2/CO2 monitor. The efficacy of the whole system has been verified through our practice as shown by the following results: measured NO inside the chamber were close to designed NO concentration, measured O2 concentrations in the chamber were similar to that of the atmosphere, and the highest nitrogen dioxide (NO2) and carbon dioxide (CO2) concentrations were lower than 3 ppm and 0.3% respectively. The experimental facility is simple in construction, easy to be operated and convenient for research on effects and toxicity of long-term inhaled nitric oxide in small animals.

摘要

设计了一种用于实验研究的一氧化氮暴露系统,该系统由有机玻璃腔室、鼓风机、流量计、一氧化氮/氮气钢瓶、纯氧钢瓶、氮氧化物分析仪和氧气/二氧化碳监测仪等设备组成。通过实践验证了整个系统的效能,结果如下:腔室内测得的一氧化氮浓度接近设计浓度,腔室内测得的氧气浓度与大气中的氧气浓度相似,二氧化氮(NO₂)和二氧化碳(CO₂)的最高浓度分别低于3 ppm和0.3%。该实验装置结构简单,易于操作,便于对小动物长期吸入一氧化氮的效果和毒性进行研究。

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