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用于全身放射自显影和β射线照相术的聚[甲基-¹⁴C]甲基丙烯酸甲酯源。

A poly[methyl-14C]methacrylate source for use in whole-body autoradiography and beta-radiography.

作者信息

Longshaw S, Fowler J S

出版信息

Xenobiotica. 1978 May;8(5):289-95. doi: 10.3109/00498257809060952.

DOI:10.3109/00498257809060952
PMID:664751
Abstract
  1. A cheap, robust, radioactive source in sheet form has been designed and constructed from commercially available material. Log-related isotopic dilutions of the source have been used to prepare a Standard Radioactive Scale. 2. The Standard Radioactive Scale has been developed as a method of internal standardization of whole-body autoradiography and its use as an aid to quantitative determination is discussed. 3. The distribution of radioactivity in the sheet source is sufficiently uniform to allow its use for high resolution radiography of thin specimens. This radiographic technique has been applied to whole body sections to demonstrate differences in quenching by tissues and to examine calcification in the rat foetus.
摘要
  1. 已使用市售材料设计并制造出一种廉价、坚固的片状放射源。该源的对数相关同位素稀释已用于制备标准放射性刻度。2. 标准放射性刻度已被开发为全身放射自显影的内部标准化方法,并讨论了其作为定量测定辅助手段的用途。3. 片状源中的放射性分布足够均匀,可用于薄标本的高分辨率射线照相。这种射线照相技术已应用于全身切片,以显示组织淬灭的差异并检查大鼠胎儿的钙化情况。

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A poly[methyl-14C]methacrylate source for use in whole-body autoradiography and beta-radiography.用于全身放射自显影和β射线照相术的聚[甲基-¹⁴C]甲基丙烯酸甲酯源。
Xenobiotica. 1978 May;8(5):289-95. doi: 10.3109/00498257809060952.
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Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development.放射自显影、MALDI-MS 和 SIMS-MS 成像在药物发现和开发中的应用。
AAPS J. 2010 Mar;12(1):11-26. doi: 10.1208/s12248-009-9158-4. Epub 2009 Nov 17.