Mueller-Klieser W, Thews G, Sutherland R M, Vaupel P
Radiat Res. 1983 Nov;96(2):411-5.
A succinct review of the terminology and of correlations between basic quantities in respiration physiology is given with special regard to oxygen as the gas of topical interest in radiation research and tumor pathophysiology. The role of the oxygen partial pressure gradient as the driving force of O2 diffusion is emphasized. It is generally recommended that the O2 partial pressure be considered when investigating oxygen diffusion and distribution problems. During those studies the physical boundary conditions, in particular the temperature, the barometric pressure, and the water vapor saturation, have to be considered and should be indicated. During equilibration of suspensions containing oxygen-consuming sites the impact of geometry and fluid agitation on the efficiency of gas exchange has to be taken into account. Reviews on solutions of diffusion equations, on numerical data for relevant constants to be considered, and on terminology and units in respiration physiology are included.
本文简要回顾了呼吸生理学中的术语以及基本量之间的相互关系,特别关注氧气,因为它是辐射研究和肿瘤病理生理学中备受关注的气体。强调了氧分压梯度作为氧气扩散驱动力的作用。一般建议在研究氧气扩散和分布问题时考虑氧分压。在这些研究中,必须考虑并指明物理边界条件,特别是温度、气压和水蒸气饱和度。在含有耗氧部位的悬浮液平衡过程中,必须考虑几何形状和流体搅拌对气体交换效率的影响。文中还包括了扩散方程解、相关常数的数值数据以及呼吸生理学中的术语和单位的综述。