Hartz A J, Giefer E E, Hoffmann R G
Stat Med. 1983 Jul-Sep;2(3):381-6. doi: 10.1002/sim.4780020310.
A number of statistics based on person-years of survival have use in mortality studies. However, calculation of an expected number of deaths based on person-years of survival and standard death rates cannot be justified. We derive a new method to estimate expected mortality based on a model which assumes that each individual contributes to expected mortality from the time he enters the study until the study ends, regardless of whether he dies during the study. This model shows that what is referred to as expected mortality in the person-years method is a biased estimate of expected mortality. The variance of observed mortality under this new model is substantially less than the variance commonly used with the person-years method.
一些基于生存人年数的统计数据在死亡率研究中有所应用。然而,基于生存人年数和标准死亡率来计算预期死亡人数是不合理的。我们推导出一种新的方法来估计预期死亡率,该方法基于一个模型,该模型假设每个个体从进入研究开始直到研究结束都对预期死亡率有贡献,无论他在研究期间是否死亡。这个模型表明,人年数方法中所谓的预期死亡率是预期死亡率的一个有偏差的估计。在这个新模型下,观察到的死亡率的方差显著小于人年数方法通常使用的方差。