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改良人脐静脉在下肢作为动脉替代物的选择性应用。

The selective use of modified human umbilical vein as an arterial substitute in the lower extremity.

作者信息

Buth J, Cohen R F, Adhin S K

出版信息

Surg Gynecol Obstet. 1983 Dec;157(6):523-9.

PMID:6648771
Abstract

Experience with 100 MHUV grafts implanted as femoropopliteal or femorocrural bypass was reviewed to evaluate the results of this conduit obtained in a selected group of patients. Indications for use of MHUV were limited to patients in whom the autologous greater saphenous vein was either absent or unsuitable or when its use would untowardly prolong the duration of the operation in patients with a poor general condition. General medical factors contributed to the choice for MHUV grafts in 25 per cent of the patients, while lack of an adequate saphenous vein necessitated its use in 70 per cent. In 5 per cent, the patient was considered a candidate for future (re)operative coronary arterial reconstruction. Cumulative graft patency rate in femoropopliteal bypass was 75 per cent in 48 months. No significant differences could be demonstrated between categories with good, fair and poor runoff or grafts with above-knee and below-knee anastomosis. In femorocrural grafts, a two year patency rate of 56 per cent was obtained. Cumulative patency rates between anterior tibial, posterior tibial and peroneal bypass did not reveal statistical differences. Late graft failure in initially jeopardized limbs without secondary reconstruction was not associated with amputation in 47 per cent of the instances. This finding reflects the fact that collateral perfusion may increase with time. On the other hand, four patients lost a leg in spite of a functioning bypass because of distally located arterial disease not amenable for reconstruction.

摘要

回顾了100例作为股腘或股胫旁路移植的低温保存脐静脉(MHUV)移植经验,以评估在一组特定患者中使用该血管 conduit 的结果。MHUV的使用指征仅限于自体大隐静脉缺失或不合适的患者,或者在全身状况较差的患者中使用大隐静脉会不适当地延长手术时间的情况。一般医学因素导致25%的患者选择MHUV移植,而70%的患者因缺乏足够的大隐静脉而必须使用它。5%的患者被认为是未来(再次)进行冠状动脉重建手术的候选人。股腘旁路移植的累积通畅率在48个月时为75%。在血流良好、一般和较差的类别之间,或膝上和膝下吻合的移植之间,未显示出显著差异。在股胫移植中,两年通畅率为56%。胫前、胫后和腓骨旁路的累积通畅率未显示出统计学差异。在最初有危险的肢体中,未经二次重建的晚期移植失败在47%的情况下与截肢无关。这一发现反映了随着时间推移侧支灌注可能增加的事实。另一方面,4例患者尽管旁路功能正常,但由于远端动脉疾病无法重建而失去了一条腿。

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Surg Gynecol Obstet. 1983 Dec;157(6):523-9.
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