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胸段食管癌根治性切除术后的复发模式

Patterns of recurrence after curative resection for carcinoma of the thoracic part of the esophagus.

作者信息

Sugimachi K, Inokuchi K, Kuwano H, Kai H, Okamura T, Okudaira Y

出版信息

Surg Gynecol Obstet. 1983 Dec;157(6):537-40.

PMID:6648774
Abstract

Two hundred patients with a previously untreated carcinoma of the thoracic portion of the esophagus and who underwent curative or noncurative resection were retrospectively evaluated. The patterns of recurrence were compared with the pathologic findings at operation. In 30 of 90 (33.3 per cent) patients in the curative resection group and 68 of 110 (61.8 per cent) of those in the noncurative resection group, there was a recurrence. Hematogenic recurrence was most frequent in instances of blood vessel invasion of the carcinoma detected at the time of the operation, and death occurred during the early postoperative period. Lymph node recurrence was most frequent in instances of lymphatic invasion or blood vessel invasion, or both, and the postoperative survival time in such patients was double that seen in those with a hematogenic-related recurrence.

摘要

对200例先前未经治疗的胸段食管癌患者进行回顾性评估,这些患者均接受了根治性或非根治性切除。将复发模式与手术时的病理结果进行比较。在根治性切除组的90例患者中有30例(33.3%)复发,非根治性切除组的110例患者中有68例(61.8%)复发。血行转移复发在手术时检测到癌组织有血管侵犯的病例中最为常见,且死亡发生在术后早期。淋巴结复发在有淋巴管侵犯或血管侵犯或两者皆有的病例中最为常见,这类患者的术后生存时间是血行转移相关复发患者的两倍。

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可视吸收光谱学作为一种生物标志物,可预测手术切除食管癌的治疗反应和预后。
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