Guzman L, Bauer S B, Hallett M, Khoshbin S, Colodny A H, Retik A B
Urology. 1983 Nov;22(5):506-10. doi: 10.1016/0090-4295(83)90230-3.
Sacral agenesis is a rare congenital anomaly of the lower vertebral column which usually produces lower urinary tract dysfunction. Sixteen children with varying degrees of sacral agenesis and urinary symptoms were extensively evaluated. The neurologic lesion varied from no denervation to a complete loss of sacral motor and sensory function. The treatment instituted was individualized and based on specific urodynamic and radiologic findings. Overall, 12 of the 16 children (75%) achieved continence. Clues to the diagnosis including symptoms, physical findings, and the relationship to maternal diabetes are discussed.
骶骨发育不全是一种罕见的下脊柱先天性异常，通常会导致下尿路功能障碍。对16例患有不同程度骶骨发育不全及泌尿系统症状的儿童进行了全面评估。神经损伤程度不一，从无神经支配到骶骨运动和感觉功能完全丧失。所采取的治疗是个体化的，基于特定的尿动力学和放射学检查结果。总体而言，16名儿童中有12名（75%）实现了控尿。文中讨论了包括症状、体格检查结果以及与母亲糖尿病的关系等诊断线索。
