[Drug-induced Quincke's edema of the mouth mucosa - an analysis of 33 cases].

Since literature only provides us with scarce information about occurrence and etiologic conditions of oro-pharyngeal Quincke's edema, we performed a retrospective evaluation of the medical records of 4,766 in-patients between the years 1970 and 1980 with registered drug-induced cutaneous and/or mucosal side effects. Among these cases there were 187 patients (= 3.92%) showing oral side effects, 33 of them with the diagnosis of Quincke's edema on the labial, oral or pharyngeal mucosa. 30 cases revealed clinical and/or historic data about concomitant occurrence of edematous lesions also in other body sites. With all patients drug intolerance was suspected by history, yet drug testings could only prove this assumption in 24 cases. Salicylates, analgetic compounds, barbiturate, pyrazolone, and penicillin are the main etiologic factors for oral Quincke's edema.